

Many women scheduled to undergo hysterectomy for pre-cancerous cell changes actually need a more comprehensive surgery, something they should discuss with a gynaecologic oncologist, say researchers at the University of Alabama at Birmingham (UAB).
If seen by a specialist, it should be recommended they undergo a procedure that focuses on lymph nodes and other organs not involved in a traditional hysterectomy, said Warner Huh, M.D., a researcher at the UAB Comprehensive Cancer Centre.
The finding was presented at the Society of Gynaecologic Oncologists' 2009 Annual Meeting on Women's Cancer in San Antonio.
'Given the high rate of endometrial cancer, these data strongly suggest all women who have abnormal bleeding and a diagnosis of pre-cancerous lesions of the uterus should be evaluated by a gynaecologic oncologist,' Huh said.
Huh and his research team analysed medical records of more than 3,322 patients treated at seven community hospitals across Alabama from 1999 to 2008. They specifically looked women diagnosed with pre-cancerous changes called complex atypical hyperplasia (CAH).
Of patients who underwent a traditional hysterectomy, about half were found to have invasive endometrial cancer after their procedure. That means too many hysterectomy patients should've had a more comprehensive cancer surgery, something a gynaecologist oncologist is trained to do, Huh said.
To avoid unwanted outcomes, women diagnosed with CAH should be referred to a gynaecologic oncologist for evaluation, he said.
Study suggests boys and girls not as different as previously thought
Mechanical regulation of cell substrates effects stem cell development, adhesion
Mining bacterial genomes reveals valuable 'hidden' drugs
Calcium connections: Basic pathway for maintaining cell's fuel stores