In women with lower urinary tract symptoms, a medical imaging technique called dynamic MRI allows clinicians to diagnose pelvic organ prolapse - a condition that often goes undiagnosed on static MRI and at physical examination, according to a study published in the December issue of the American Journal of Roentgenology.
Pelvic organ prolapse is relatively common and occurs when the pelvic floor muscles become weak or damaged and can no longer support the pelvic organs. If left untreated, living with prolapse can be a challenge, both physically and emotionally, as the symptoms can disrupt day-to-day life. Dynamic MRI is performed while the patient performs a straining manoeuvre, such as bearing down. Static MRI is performed while the patient is at rest.
The study, performed at NYU Langone Medical Centre in New York, included 84 women with lower urinary tract symptoms who underwent dynamic and static MRI scans for a suspected urethra abnormality. Ten of the 84 patients were found to have an abnormality of the urethra. 'However 33 patients were diagnosed with pelvic organ prolapse, of whom 29 were diagnosed exclusively on dynamic imaging,' said Genevieve L. Bennett, M.D., assistant professor of radiology at NYU Langone Medical Centre and lead author of the study.
'Dynamic imaging allows for the detection of pelvic organ prolapse, which may not be evident at rest but only detected when the woman strains,' said Bennett.
'The results of our study show that in women with lower urinary tract symptoms who undergo MRI for evaluation of a suspected urethra abnormality, the addition of dynamic MRI permits detection of pelvic organ prolapse that may not be evident on static at rest images and that may also go undetected at physical examination,' she said.
How diarrhoeal bacteria cause some colon cancersJohns Hopkins scientists say they have figured out how bacteria that cause diarrhoea may also be the culprit in some colon cancers. The investigators say that strains of the common... — full story
Inherited risk factors increase odds of developing childhood acute lymphoblastic leukaemiaScientists at St. Jude Children's Research Hospital have identified inherited variations in two genes that account for 37 percent of childhood acute lymphoblastic leukaemia (ALL), including... — full story
Scientists create energy-burning brown fat in miceResearchers at Dana-Farber Cancer Institute have shown that they can engineer mouse and human cells to produce brown fat, a natural energy-burning type of fat that counteracts obesity.... — full story
Genome of parasitic flatworm that causes schistosomiasis decodedAn international team of scientists has sequenced the genome of Schistosoma mansoni, a parasitic worm, commonly known as a blood fluke, that infects 210 million in 76 countries through... — full story