Genes make up only a tiny percentage of the human genome. The rest, which has remained measurable but mysterious, may hold vital clues about the genetic origins of disease. Using a…
Scientists today published catalogues of the fruit fly and roundworm's functional genomic elements: DNA sequences in the genome that carry the instructions and determine which genes…
The function of histones - the proteins that enable yards of DNA to be crammed into a single cell - depends on a number of chemical tags adorning their exterior. This sophisticated…
In a study published in the journal Developmental Cell, Sarah Millar PhD, professor of Dermatology and Cell and Developmental Biology at the University of Pennsylvania School of Medicine,…
A team led by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, has captured the most comprehensive snapshot to date of…
A new study reveals that two enzymes help immune cells deploy pathogen-killing traps by unravelling and using the chromatin (DNA and its associated proteins) contained in the cells'…
A team led by a scientist at the University of Pittsburgh School of Medicine has discovered a regulatory protein that influences where genetic material gets swapped between maternal…
Like cats, human cells have a finite number of lives-once they divide a certain number of times (thankfully, more than nine) they change shape, slow their pace, and eventually stop…
In the quest to arrest the growth and spread of tumours, there have been many attempts to get cancer genes to ignore their internal instruction manual. In a new study, a team led by…
Scientists at the Johns Hopkins Kimmel Cancer Centre have identified two genes whose mutations appear to be linked to ovarian clear cell carcinoma, one of the most aggressive forms…