Cells control which genes they express by multiple mechanisms, one of which is the direct modification of DNA with small molecules. Methylation of genes effectively silences them, and…
A new study uncovers a previously unrecognised link between tobacco smoking and a gene known to influence the cardiovascular system, possibly identifying an early stage of smoking-associated…
Knowing that it is impossible to catalogue all the carcinogenic exposures a person has had in life and then assess them, Brown University researcher Carmen Marsit is looking for a more…
Reprogramming adult cells to recapture their youthful 'can-do-it-all' attitude appears to leave an indelible mark, found researchers at the Salk Institute for Biological Studies. When…
A new study provides insight into how stress impacts the brain and may help to explain why some individuals are predisposed to depression when they experience chronic stress. The research,…
A new study shows that a test of biomarkers for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma…
Fat appears to associate with some distinctive chemical changes in the DNA - a finding that may help explain why obesity can increase the risk for chronic problems such as cardiovascular…
People with higher levels of folate in their red blood cells were more likely to have two tumour-suppressing genes shut down by methylation, a chemical off switch for genes, researchers…
A newly published insight into the biology of many kinds of less-aggressive but still lethal brain tumours, or gliomas, opens up a wide array of possibilities for new therapies, according…
There are many mechanisms that alter the activity of genes - direct changes to the DNA code like mutations and deletions, or changes that control when genes are switched on and off,…