Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress from precursor to progeny, a Johns Hopkins-led team of scientists…
A subtle mutation affecting the epigenome - a set of dynamic factors that influence gene activity - may lead to an inherited form of mental retardation that affects boys, find researchers…
Transposons, or 'jumping genes,' make up roughly half of the human genome. Geneticists previously estimated that they replicate and insert themselves into new locations roughly one…
The combination of decitabine and carboplatin appears to improve the outcome of women who have late-stage ovarian cancer. In an upcoming issue of the journal Cancer (online today),…
A rare but fatal disease of blood vessels in the lung may be caused in part by aberrant silencing of genes rather than genetic mutation, new research reports…
A gene shown to play a role in the ageing process appears to play a role in the regulation of the differentiation of embryonic stem cells, according to researchers from the Centre for…
A previously unknown pattern in DNA methylation - an event that affects cell function by altering gene expression - has been uncovered for the first time by stem cell researchers at…
Chemical changes in the genetic material, known as epigenetic modifications, regulate the activity of many genes. Thus, attachment of methyl groups to DNA often inactivates important…
A study by researchers at Columbia University's Mailman School of Public Health suggests that traumatic experiences 'biologically embed' themselves in select genes, altering their functions…
A study conducted by a collaborative team led by researchers from the University of Southern California (USC) may lead to better insight into the clinical outcome for some patients…