News articles tagged with 'mutant'
Old drugs find new target for treating brain tumour
— 19 Nov 2011 15:50 | HealthScientists at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Centre, in collaboration with colleagues in Boston and South Korea, say they…
Huntington's disease protein has broader effects on brain, study shows
— 6 Apr 2011 17:28 | HealthIn Huntington's disease, the mutant protein known as huntingtin leads to the degeneration of a part of the brain known as the basal ganglia, causing the motor disturbances that represent…
Mutant prions help cells foil harmful protein misfolding
— 21 Mar 2011 15:37 | HealthRomping clumps of misfolded proteins are prime suspects in many neurological disorders including Alzheimer's, Parkinson's, and Creutzfeld-Jakob Disease. Those diseases are devastating…
Scientists probe the role of motor protein in hearing loss
— 7 Mar 2011 16:58 | HealthFrom grinding heavy metal to soothing ocean waves, the sounds we hear are all perceptible thanks to the vibrations felt by tiny molecular motors in the hair cells of the inner ear.…
Nature Reviews Cancer article traces possible role of damaged DNA in tumour development
— 5 Mar 2011 13:27 | HealthDNA provides the instruction manual for all life forms. Occasionally, instructions are not carried out properly, and bad messages are sent leading to the creation of mutant proteins…
New research suggests that obesity and diabetes are a downside of human evolution
— 26 Feb 2011 17:18 | HealthAs if the recent prediction that half of all Americans will have diabetes or pre-diabetes by the year 2020 isn't alarming enough, a new genetic discovery published online in the FASEB…
How disordered proteins spread from cell to cell, potentially spreading disease
— 19 Feb 2011 10:21 | HealthOne bad apple is all it takes to spoil the barrel. And one misfolded protein may be all that's necessary to corrupt other proteins, forming large aggregations linked to several incurable…
Scientists used accelerated evolution to develop enzymes that provide protection against nerve gas
— 24 Jan 2011 15:13 | HealthProtection against nerve gas attack is a significant component of the defence system of many countries around the world. Nerve gases are used by armies and terrorist organisations,…
Missing molecules hold promise of therapy for pancreatic cancer
— 16 Dec 2010 17:46 | HealthBy determining what goes missing in human cells when the gene that is most commonly mutated in pancreatic cancer gets turned on, Johns Hopkins scientists have discovered a potential…
Stability is first step toward treating ALS
— 23 Nov 2010 16:56 | HealthAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that eventually destroys most motor neurones, causing muscle weakness and atrophy throughout the body. There…