In analysing the molecular sensor for the plant growth hormone brassinolide, researchers at the Salk Institute for Biological Studies discovered that although plants took an evolutionary…
Metformin, a drug used in type 2-diabetes might have the potential to also act against Alzheimer's disease. This has been shown in a study from scientists of the German Centre for Neurodegenerative…
Cells that help to protect the central nervous system may also contribute to pathological changes in the brain. New research, published by Cell Press in the October 7th issue of the…
Many genes code for proteins that have a 'polyglutamine tract,' several glutamine amino acid residues in a row. Nine inherited neurodegenerative diseases, including Huntington's disease…
Researchers at Beth Israel Deaconess Medical Centre (BIDMC) have uncovered the genes that regulate MDM2, an oncogene that, in turn, regulates the tumour suppressor protein p53. But…
A kinase is a type of enzyme the body uses to regulate the functions of the proteins required for cell growth and maintenance, and researchers have discovered that one in particular…
Like a scout that runs ahead to spot signs of damage or danger, a protein in yeast safeguards the yeast cells' genome during replication - a process vulnerable to errors when DNA is…
A new understanding of insulin resistance and the action of diabetes drugs such as Avandia and Actos could pave the way for improved medications that are more selective and safer, say…
In a joint study, scientists from The Scripps Research Institute and the Dana-Farber Cancer Institute at Harvard University have uncovered a novel mechanism that dramatically increases…
A protein that helps pack DNA into the cell nucleus has an important role in regulating gene activity, scientists report. The researchers found that the protein, histone H1, also takes…