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Tracking down the origin of leukaemia relapse
— 4 Apr 2011 18:30 | HealthThe cancer cells that reign during relapses of an aggressive human leukaemia are different from those that dominated the original disease, according to a paper published online on April…
T cells outpace virus by getting a jump-start on division
— 4 Apr 2011 18:27 | HealthKiller T cells begin to divide en route to virus-infected tissue, allowing them to hit the ground running when they arrive, according to a study published online on April 4 in the Journal…
Osteoblasts are bone idle without Frizzled-9
— 14 Mar 2011 20:00 | HealthNew research shows that the Wnt receptor Frizzled-9 (Fzd9) promotes bone formation, providing a potential new target for the treatment of osteoporosis. The study appears online on March…
Researchers define a new type of secretory cell in the intestine
— 8 Mar 2011 14:53 | HealthThe intestinal epithelium consists of four main specialised cell lineages: absorptive enterocytes and three secretory cell types known as enteroendocrine, Paneth, and goblet cells.…
Parkinson's disease may be caused by microtubule, rather than mitochondrial complex I, dysfunction
— 8 Mar 2011 14:50 | HealthPatients with Parkinson's disease (PD) suffer a specific loss of dopaminergic neurones from the midbrain region that controls motor function. The exact mechanism of this selective neurodegeneration…
Gene variant affects stroke prognosis in humans
— 1 Mar 2011 18:18 | HealthA small difference in DNA sequence predicts the degree of disability after a stroke, according to a paper published online on February 28 in the Journal of Experimental Medicine (www.jem.org).…
Protein fuels inflammation in pancreatic and breast tumours
— 22 Feb 2011 23:40 | HealthSeparate studies published online on February 21 in the Journal of Experimental Medicine (www.jem.org) identify a protein that drives tumour-promoting inflammation in pancreatic and…
Unappreciated dynamism of blood cell production
— 8 Feb 2011 18:33 | HealthThe bone marrow stem cells responsible for generating new blood cells are less fixed and more flexible than previously thought, according to a paper published online on February 7 in…
Preventing GVHD by protecting gut stem cells
— 1 Feb 2011 21:43 | HealthA protein that protects stem cells in the gut relieves a potentially lethal complication of bone marrow transplantation in mice, according to a study published online on January 31…
Cells' energy factories linked to damaging inflammation
— 1 Feb 2011 21:43 | HealthScientists have discovered that molecules called reactive oxygen species (ROS) produced by the energy factories, or mitochondria, in cells, may play a role in a rare inherited disorder…